摘要: In contrast to the majority of other genetic cancer syndromes reviewed in this book, neurofibromatosis 1 (NF1) and 2 (NF2) do not result development affected individuals. NF1, tumours which develop patients are benign cutaneous neurofibromas. People with NF1 have a small but significant risk specific cancers include peripheral nerve sarcomas, rhabdomyosarcomas, atypical forms childhood leukaemia astrocytomas. NF2, nearly always histologically vestibular schwannomas (also called acoustic neuromas), meningiomas, spinal ependymomas. Although these malignant, curative surgery is often difficult NF2 associated disease-related morbidity mortality.
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