Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB

作者: Bernard Khoo , Xavier Roca , Shern L Chew , Adrian R Krainer

DOI: 10.1186/1471-2199-8-3

关键词:

摘要: … Our work relies on 2'O-methyl RNA oligonucleotides as splice-site ASOs, and joins a growing list of synthetic nucleic acid-based compounds that have been used to modify splicing [40]. …

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