New drugs with antiprotozoal activity from marine algae: a review

摘要: The use of indigenous or remote popular knowledge to identify new drugs against diseases infections is a well-known approach in medicine. inhabitants coastal regions are known prepare algae extracts for the treatment disorders and ailments such as wounds, fever stomach aches, prevention arrhythmia. Recent trends drug research from natural sources have indicated that marine promising source novel biochemically active compounds, especially with antiprotozoal activity. Algae survive competitive environment and, therefore, developed defense strategies resulted significant level chemical structural diversity various metabolic pathways. exploration these organisms pharmaceutical medical purposes has provided important candidates discovery agents neglected tropical diseases, stimulating sophisticated physical techniques. This current review describes main substances biosynthesized by benthic activity Leishmania spp., Trypanosoma cruzi brucei; causative leishmaniasis, Chagas disease African trypanosomiasis, respectively. Emphasis given secondary metabolites crude prepared algae.