Are osteoporotic fractures due to osteoporosis? Impacts of a frailty pandemic in an aging world.

摘要: Osteoporosis is a major risk factor for fractures in the elderly. Osteoporotic (hip, forearm, and vertebral) today strike hard on Western populations, with lifetime women similar to cardiovascular disease. The of dying from hip fracture equals breast cancer mortality. are associated pain, crippling social dependency; annual costs United States between $7 $20 billion, contribution above 60%. Of all hospital beds Europe, 1 1.5% occupied by osteoporotic patients, figure expected more than double during next fifty years. Whereas vertebral mainly seem be caused osteoporosis alone, heavily affected an age-dependent contributory factor, frailty. Frailty might act as involutionary phenomenon or comorbidity, particularly neurological; it affects along several causal paths, but increasing frequency severity falls essential. Results attempts prevent discouragingly poor. Nevertheless, identification possessors, demented elderly living institutions, substantial directing preventive treatment programs, acting general health osteoporosis. populations increases longevity. Consequently, projections occurrence too conservative. incidence Asia 2050 pass 10 million, rather hitherto forecasted 3.2 thus shifting tomorrow’s burden age-related wealthier poorer countries. There immediate call vigorous global actions reallocate resources, reorganize care, institute high-risk prevention programs.