A noninvasive method for measuring portal venous/total hepatic blood flow by hepatosplenic radionuclide angiography.

摘要: Radionuclide angiography was used to generate first-pass radioactivity vs. time curves for the left heart, right hepatic lobe, lung, spleen, and both kidneys following rapid intravenous injection of 20 mCi (740 MBq) 99mTc-pertechnetate. Seven normal subjects were examined as well 57 cirrhotic patients, who also underwent angiographic grading portal venous perfusion. For analysis, two points identified: (a) t0, when 99mTc first entered liver (the initial rise either curve); (b)tc, maximal in abdominal organs renal peak). Analysis based on slopes phases t0 + 7 seconds Tc seconds; this selection permitted analysis all curves. The perfusion index (HPI) = slope (tc secs)/slope (t0 secs) secs). mean HPI 66% +/- 7; patients with Grades I, II, III, IV, 52% 9, 37% 6, 15% 7, 3% +...