Functional gastrointestinal disorders and mood disorders in patients with inactive inflammatory bowel disease: prevalence and impact on health.

作者: Forough Farrokhyar , John K Marshall , Brock Easterbrook , Jan E Irvine

DOI: 10.1097/01.MIB.0000195391.49762.89

关键词:

摘要: Background: Symptoms of functional gastrointestinal disorders (FGID) associated with mood (MD), such as depression and anxiety, occur in some patients quiescent inflammatory bowel disease (IBD) could be caused by changes gut motility, visceral hypersensitivity, or psychological dysfunction. We assessed the prevalence FGID symptoms ambulatory IBD examined their impact on health-related quality life (HRQOL) use health resources. Methods: Consecutive completed a survey Rome II criteria for FGID, Hospital Anxiety Depression Survey, HRQOL indices, resource utilization. Logistic linear regression analyses tested predictors HRQOL. Results: Of 361 surveyed, 149 (44 ulcerative colitis [UC] 105 Crohn's [CD]) had inactive during previous 12 months. at least 1 occurred 81.9%. Functional anorectal were most prevalent (53.7%) followed (51.7%), both greater than Canadian population (41.6% 22.6%, respectively). Irritable syndrome more common CD UC (26% versus 9.1%, P = .01) constipation was (26.2% 5.8%, < .01). MD 27.3% 31.3% patients. Age ≥40 years anxiety independently predicted an FGID. Both impaired increased services. Conclusions: Many have compatible FGID-like are Recognition treatment potentially improve daily functioning

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