摘要: Traditionally, orthopedists have not evaluated the quality of bone prior to orthopedic procedures. Nonetheless, in recent years an assortment pharmacological agents targeting been developed and are common use, mainly treatment osteoporosis. Growing evidence suggests that maximization health perioperatively will result better surgical outcomes. This chapter reviews current knowledge concerning this clinical experience, examining specifically vitamin D, its putative role surgery; use various medications setting total joint arthroplasty, spinal fusion, fracture repair is presented.