Perceived stress in prodromal Huntington disease.
作者： Nancy Downing , Megan M Smith , Leigh J Beglinger , James Mills , Kevin Duff
DOI: 10.1080/08870446.2010.529141
关键词:
摘要: This study examines perceived stress and its relationship to depressive symptoms, life changes functional capacity in a large sample of individuals who are positive for the Huntington disease (HD) gene expansion but not yet diagnosed. Participants were classified by estimated proximity HD diagnosis (far, mid, near) compared with non-gene-expanded comparison group. Persons mid group had highest scores. A significant interaction between age time since genetic testing was also found. Secondary analyses using data from different collection point including diagnosed showed scores Possible explanations implications discussed.
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