Interactions of HIV-1 proteins as targets for developing anti-HIV-1 peptides

作者: Koushik Chandra , Michal Maes , Assaf Friedler

DOI: 10.4155/FMC.15.46

关键词:

摘要: Protein–protein interactions (PPI) are essential in every step of the HIV replication cycle. Mapping between viral and host proteins is a fundamental target for design development new therapeutics. In this review, we focus on rational anti-HIV-1 peptides based mapping viral–host viral–viral protein all across HIV-1 We also discuss mechanism action, specificity stability these peptides, which designed to inhibit PPI. Some excellent tools study mechanisms PPI cycle drug leads that modulate

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