The effect of rilonacept versus placebo on health-related quality of life in patients with poorly controlled familial Mediterranean fever
作者： Philip J. Hashkes , Steven J. Spalding , Rula Hajj-Ali , Edward H. Giannini , Anne Johnson
DOI: 10.1155/2014/854842
关键词:
摘要: Objective. To examine the effect of rilonacept on health-related quality life (HRQoL) in patients with poorly controlled familial Mediterranean fever (FMF). Methods. As part a randomized, double-blinded trial comparing and placebo for treatment FMF, patients/parents completed modified Child Health Questionnaire (CHQ) at baseline, start end each 4 courses, 2 placebo. Results. Fourteen subjects were randomized; mean age was 24.4 ± 11.8 years. At baseline physical HRQoL score significantly less (24.2 49.5) but psychosocial similar to population norm (49.5 10.0). There significant improvements most concepts after not Significant differences between found (33.7 16.4 versus 23.7 14.5, P = 0.021) scores (51.4 10.3 49.8 12.4, 0.42). The impacted by patient global assessment. Conclusion. Treatment had beneficial FMF also related This is registered ClinicalTrials.gov Identifier NCT00582907.
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