Wuchereria bancrofti infection in human and mosquito populations of a Polynesian village ten years after interruption of mass chemoprophylaxis with diethylcarbamazine

摘要: Abstract In 1991, a study on Wuchereria bancrofti microfilariae (mf) and infection rates was carried out in the human mosquito populations of Polynesian village where, 10 years before, mf prevalence rate 6·4% twice-yearly mass treatment with 3 mg/kg diethylcarbamazine (DEC) interrupted. Venous blood samples were collected from 575 (97%) individuals aged 15 or more, whom 122 (21·4%) positive. The carrier 27·4% males, significantly higher than that 14% females; it increased 7–12% youngest age group (15–19 years) to 40–50% oldest (⩾60 for both males females. 387 collections performed 1748 female Aedes polynesiensis dissected, which 1176 parous. Among latter, 114 (9·7%) infected larvae at L1, L2 L3 stages. mean number per 2·46 (range 1–15). Of mosquitoes, 30 harboured larvae, giving 2·55% infective rate; 1·15 1–2). Such findings indicate interruption systematic twiceyearly DEC (3 mg/kg) has resulted, after years, substantial increase microfilarial humans, high mosquitoes.