Prognostic relevance of systematic lymph node dissection in gastric carcinoma. German Gastric Carcinoma Study Group.

作者: J. R. Siewert , K. Böttcher , J. D. Roder , R. Busch , P. Hermanek

DOI: 10.1002/BJS.1800800829

关键词:

摘要: In a prospective multicentre study of 2394 patients with gastric carcinoma the prognostic relevance systematic lymph node dissection was evaluated. Of 1654 undergoing resection, 558 had standard dissection, defined as fewer than 26 nodes in specimen, and 1096 underwent radical lymphadenectomy, i.e. or more specimen. Radical significantly improved survival rate Union Internacional Contra la Cancrum (UICC) stages II IIIA tumours. Multivariate analysis identified an independent factor subgroups UICC tumour IIA. conferred no advantage pN2 There significant difference morbidity mortality rates between dissection. lymphadenectomy improves cancer IIIA, should be recommended treatment for such patients.

参考文章(13)
TNM classification of malignant tumours Published in <b>2010</b> in Chichester, West Sussex, UK ;Hoboken, NJ by Wiley-Blackwell. ,(1987) , 10.1007/978-3-642-82982-6
D. M. Dent, M. V. Madden, S. K. Price, Randomized comparison of R1 and R2 gastrectomy for gastric carcinoma. British Journal of Surgery. ,vol. 75, pp. 110- 112 ,(2005) , 10.1002/BJS.1800750206
J. R. Siewert, J. Lange, K. B�ttcher, Karen Becker, A. Stier, Lymphadenectomy in stomach cancer Langenbeck's Archives of Surgery. ,vol. 368, pp. 137- 148 ,(1986) , 10.1007/BF01273852
Keiichi Maruyama, Kenzo Okabayashi, Taira Kinoshita, Progress in gastric cancer surgery in Japan and its limits of radicality. World Journal of Surgery. ,vol. 11, pp. 418- 425 ,(1987) , 10.1007/BF01655804
Joachim Jaehne, Lymphadenectomy in Gastric Carcinoma Archives of Surgery. ,vol. 127, pp. 290- 294 ,(1992) , 10.1001/ARCHSURG.1992.01420030052010
P. K. Wagner, A. Ramaswamy, J. Rüschoff, P. Schmitz-Moormann, M. Rothmund, Lymph node counts in the upper abdomen: Anatomical basis for lymphadenectomy in gastric cancer British Journal of Surgery. ,vol. 78, pp. 825- 827 ,(2005) , 10.1002/BJS.1800780719
Ron Brookmeyer, John Crowley, A Confidence Interval for the Median Survival Time Biometrics. ,vol. 38, pp. 29- ,(1982) , 10.2307/2530286