作者: Susan M. Patterson , Carmel M. Hughes , Grainne Crealey , Chris Cardwell , Kate L. Lapane
DOI: 10.1111/J.1532-5415.2009.02617.X
关键词:
摘要: OBJECTIVES: To test the effect of an adapted U.S. model pharmaceutical care on prescribing inappropriate psychoactive (anxiolytic, hypnotic, and antipsychotic) medications falls in nursing homes for older people Northern Ireland (NI). DESIGN: Cluster randomized controlled trial. SETTING: Nursing to intervention (receipt care; n=11) or control (usual continued; n=11). PARTICIPANTS: Residents aged 65 who provided informed consent (N=334; 173 intervention, 161 control). INTERVENTION: Specially trained pharmacists visited monthly 12 months reviewed residents' clinical information, applied algorithm that guided them assessing appropriateness medication, worked with prescribers (general practitioners) improve these drugs. The received usual care. MEASUREMENTS: primary end point was proportion residents prescribed one more medicine according standardized protocols; were evaluated using routinely collected data mandated by regulatory body NI. RESULTS: taking at (25/128, 19.5%) much lower than (62/124, 50.0%) (odds ratio=0.26, 95% confidence interval=0.14–0.49) after adjustment clustering within homes. No differences observed rate between groups. CONCLUSION: Marked reductions medication resulted from pharmacist review targeted medications, but there no falls.