Challenging regional psoriasis and ustekinumab biotherapy: impact of the patterns of disease.
作者： Trinh Hermanns-Lê , Enzo Berardesca , Gérald E. Piérard , Marianne Lesuisse , Claudine Piérard-Franchimont
DOI: 10.1155/2012/413767
关键词:
摘要: In some patients, psoriasis appears refractory to many treatments, particularly when the disease is confined specific body regions. this respect, palmoplantar and pustulosis are possibly related conditions in their immunopathomechanisms involving Il-12, IL-23, Th17. Nail scalp two other particular manifestations. Accordingly, ustekinumab was tested a few of these patients. The present paper limited peer-reviewed case reports. Data were not supported by bioinstrumental assessments controlled trials. Overall, they indicative potential efficacy. cost-effectiveness risk-benefit merit further investigations.
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