作者: E. Folléanius , J. Doerr-Schott , M.P. Dubois
DOI: 10.1016/S0074-7696(08)60168-0
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摘要: Publisher Summary Two major contributions have been made through immunocytological studies of fish pituitaries and immunochemical assays the corresponding hormones. The first demonstrates one-hormone, one-cell-type principle for several ACTH-, PRL-, GH-like hormones are found in easily localized cells. Some difficulties encountered establishing an distinction between two gonadotropic with immunocytology. This failure to identify distinct pituitary species is a further indication that, at least this group, only one substance present. other problems concern thyrotropic In case, may be related presence common subunit both hormones, but explanation has verified by biochemical analysis second main contribution that even greater potential future investigations, concerns demonstration characteristics different vertebrate more or less illustrated similar biological activities bioassay systems, also include immunological similarities. due determinants throughout groups. Evolution from molecule hypothesis best explains similarities differences among