Gymnemic Acid Stimulates In Vitro Splenic Lymphocyte Proliferation.
作者： Vineet Kumar Singh , Padmanabh Dwivedi , B. R. Chaudhary , Ramesh Singh
DOI: 10.1002/PTR.5514
关键词:
摘要: Gymnemic acid is a mixture of triterpenoid saponins oleanane class, isolated from Gymnema sylvestre Wild R.Br (family: Asclepidaceae), an herbal plant used in traditional medicine to treat diabetes. Effect gymnemic (0.1–20 µg/mL) on vitro mitogen (concanavalin A and lipopolysaccharide)-induced splenic lymphocyte proliferation was studied using rat as model. Significant (p < 0.05) stimulation lymphoproliferation observed cultures treated with 10 20 µg/mL concentration the absence or presence mitogens. The present study suggests that has immunomodulatory property, stimulating lymphoid components immune system, knowledge anti-diabetic property G. sylvestre scientifically supplemented its properties. Copyright © 2015 John Wiley & Sons, Ltd.
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