InCl3·4H2O-promoted green preparation of xanthenedione derivatives in ionic liquids

作者: Xuesen Fan , Xueyuan Hu , Xinying Zhang , Jianji Wang

DOI: 10.1139/V04-155

关键词:

摘要: A green procedure for the synthesis of xanthenedione derivatives (3) through InCl3·4H2O-promoted condensation aldehydes (1) and 5,5-dimethyl-1,3-cyclohexanedione (2) in ionic liquids is described this paper. This novel method has such advantages as operational simplicity environmental benignancy together with enhanced atom utilization. Moreover, reaction media catalyst can be recovered conveniently reused effectively at least six times.Key words: liquid, derivatives, indium trichloride, synthesis.

参考文章(6)
Sankar Chatterjee, Mohamed Iqbal, James C. Kauer, John P. Mallamo, Shobha Senadhi, Satish Mallya, Donna Bozyczko-Coyne, Robert Siman, Xanthene derived potent nonpeptidic inhibitors of recombinant human calpain I Bioorganic & Medicinal Chemistry Letters. ,vol. 6, pp. 1619- 1622 ,(1996) , 10.1016/S0960-894X(96)00286-7
Jürgen Wichmann, Konrad Bleicher, Eric Vieira, Thomas Woltering, Frédéric Knoflach, Vincent Mutel, Alkyl diphenylacetyl, 9H-xanthene- and 9H-thioxanthene-carbonyl carbamates as positive allosteric modulators of mGlu1 receptors. Farmaco. ,vol. 57, pp. 989- 992 ,(2002) , 10.1016/S0014-827X(02)01283-1
Jairton Dupont, Roberto F. de Souza, Paulo A. Z. Suarez, Ionic liquid (molten salt) phase organometallic catalysis. Chemical Reviews. ,vol. 102, pp. 3667- 3692 ,(2002) , 10.1021/CR010338R
Yasumasa Hamada, Fumiyoshi Matsuura, Makoto Oku, Keiichiro Hatano, Takayuki Shioiri, SYNTHESIS AND APPLICATION OF NEW CHIRAL BIDENTATE PHOSPHINE, 2,7-DI-TERT-BUTYL-9,9-DIMETHYL-4,5-BIS(METHYLPHENYLPHOSPHINO)XANTHENE Tetrahedron Letters. ,vol. 38, pp. 8961- 8964 ,(1997) , 10.1016/S0040-4039(97)10363-X