Venous Thromboembolism in Critically Ill Patients with Covid-19: Results of a Screening Study for Deep Vein Thrombosis
作者： Alban Longchamp , Justine Longchamp , Sara Manzocchi‐Besson , Livia Whiting , Claude Haller
DOI: 10.1002/RTH2.12376
关键词:
摘要: Background The rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and disease 2019 (COVID-19), has caused more than 3.9 million cases worldwide. Currently, there is great interest to assess venous thrombosis prevalence, diagnosis, prevention, management in patients with COVID-19. Objectives To determine prevalence thromboembolism (VTE) critically ill COVID-19, using lower limbs ultrasonography screening. Methods Beginning March 8, we enrolled 25 who were admitted intensive care unit (ICU) confirmed SARS-CoV-2 infections. presence extremity deep vein (DVT) was systematically assessed by between day 5 10 after admission. data reported here are those available up May 9, 2020. Results mean (± standard deviation) age 68 ± 11 years, 64% men. No had a history VTE. During ICU stay, 8 (32%) VTE; 6 (24%) proximal DVT, (20%) pulmonary embolism. rate symptomatic VTE 24%, while 8% screen-detected DVT. Only documented received therapeutic anticoagulant regimen. As 2020, died (20%), remained (8%), 18 discharged (72%). Conclusions In infections, DVT screening at days 5-10 admission yielded 32% Seventy-five percent events occurred before Earlier might be effective optimizing
scilit.net参考文章(18)
Fletcher Taylor, Cheng-Hock Toh, Keith Hoots, Hideo Wada, Marcel Levi, Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thrombosis and Haemostasis. ,vol. 86, pp. 1327- 1330 ,(2001) , 10.1055/S-0037-1616068
Acute respiratory distress syndrome: the Berlin Definition. JAMA. ,vol. 307, pp. 2526- 2533 ,(2012) , 10.1001/JAMA.2012.5669
Pek Yoon Chong, Paul Chui, Ai E Ling, Teri J Franks, Dessmon YH Tai, Yee Sin Leo, Gregory JL Kaw, Gervais Wansaicheong, Kwai Peng Chan, Lynette Lin Ean Oon, Eng Swee Teo, Kong Bing Tan, Noriko Nakajima, Tetsutaro Sata, William D Travis, None, Analysis of deaths during the severe acute respiratory syndrome (SARS) epidemic in Singapore: challenges in determining a SARS diagnosis. Archives of Pathology & Laboratory Medicine. ,vol. 128, pp. 195- 204 ,(2004) , 10.1043/1543-2165(2004)128<195:AODDTS>2.0.CO;2
Susan R. Kahn, Wendy Lim, Andrew S. Dunn, Mary Cushman, Francesco Dentali, Elie A. Akl, Deborah J. Cook, Alex A. Balekian, Russell C. Klein, Hoang Le, Sam Schulman, M. Hassan Murad, Prevention of VTE in Nonsurgical Patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines Chest. ,vol. 141, ,(2012) , 10.1378/CHEST.11-2296
John Attia, Joel G. Ray, Deborah J. Cook, James Douketis, Jeffrey S. Ginsberg, William H. Geerts, Deep Vein Thrombosis and Its Prevention in Critically Ill Adults JAMA Internal Medicine. ,vol. 161, pp. 1268- 1279 ,(2001) , 10.1001/ARCHINTE.161.10.1268
Anthonie W.A. Lensing, Paolo Prandoni, Dees Brandjes, Peter M. Huisman, Mario Vigo, Giovanni Tomasella, Jelmer Krekt, Jan Wouter ten Cate, Menno V. Huisman, Harry R. Büller, Detection of Deep-Vein Thrombosis by Real-Time B-Mode Ultrasonography New England Journal of Medicine. ,vol. 320, pp. 342- 345 ,(1989) , 10.1056/NEJM198902093200602
Stavros V Konstantinides, Guy Meyer, Cecilia Becattini, Héctor Bueno, Geert-Jan Geersing, Veli-Pekka Harjola, Menno V Huisman, Marc Humbert, Catriona Sian Jennings, David Jiménez, Nils Kucher, Irene Marthe Lang, Mareike Lankeit, Roberto Lorusso, Lucia Mazzolai, Nicolas Meneveau, Fionnuala Ní Áinle, Paolo Prandoni, Piotr Pruszczyk, Marc Righini, Adam Torbicki, Eric Van Belle, José Luis Zamorano, Nazzareno Galié, J Simon R Gibbs, Victor Aboyans, Walter Ageno, Stefan Agewall, Ana G Almeida, Felicita Andreotti, Emanuele Barbato, Johann Bauersachs, Andreas Baumbach, Farzin Beygui, Jørn Carlsen, Marco De Carlo, Marion Delcroix, Victoria Delgado, Pilar Escribano Subias, Donna Fitzsimons, Sean Gaine, Samuel Z Goldhaber, Deepa Gopalan, Gilbert Habib, Sigrun Halvorsen, David Jenkins, Hugo A Katus, Barbro Kjellström, Mitja Lainscak, Patrizio Lancellotti, Geraldine Lee, Grégoire Le Gal, Emmanuel Messas, Joao Morais, Steffen E Petersen, Anna Sonia Petronio, Massimo Francesco Piepoli, Susanna Price, Marco Roffi, Aldo Salvi, Olivier Sanchez, Evgeny Shlyakhto, Iain A Simpson, Stefan Stortecky, Matthias Thielmann, Anton Vonk Noordegraaf, Cecilia Becattini, Héctor Bueno, Geert-Jan Geersing, Veli-Pekka Harjola, Menno V Huisman, Marc Humbert, Catriona Sian Jennings, David Jiménez, Nils Kucher, Irene Marthe Lang, Mareike Lankeit, Roberto Lorusso, Lucia Mazzolai, Nicolas Meneveau, Fionnuala Ní Áinle, Paolo Prandoni, Piotr Pruszczyk, Marc Righini, Adam Torbicki, Eric VanBelle, José LuisZamorano, Stephan Windecker, Victor Aboyans, Colin Baigent, Jean-Philippe Collet, Veronica Dean, Victoria Delgado, Donna Fitzsimons, Chris P Gale, Diederick Grobbee, Sigrun Halvorsen, Gerhard Hindricks, Bernard Iung, Peter Jüni, Hugo A Katus, Ulf Landmesser, Christophe Leclercq, Maddalena Lettino, Basil S Lewis, Bela Merkely, Christian Mueller, Steffen E Petersen, Anna Sonia Petronio, Dimitrios J Richter, Marco Roffi, Evgeny Shlyakhto, Iain A Simpson, Miguel Sousa-Uva, Rhian M Touyz, Naima Hammoudi, Hamlet Hayrapetyan, Julia Mascherbauer, Firdovsi Ibrahimov, Oleg Polonetsky, Patrizio Lancellotti, Mariya Tokmakova, Bosko Skoric, Ioannis Michaloliakos, Martin Hutyra, Søren Mellemkjaer, Mansour Mostafa, Julia Reinmets, Pertti Jääskeläinen, Denis Angoulvant, Johann Bauersachs, George Giannakoulas, Endre Zima, Carmine Dario Vizza, Akhmetzhan Sugraliyev, Ibadete Bytyçi, Aija Maca, Egle Ereminiene, Steve Huijnen, Robert Xuereb, Nadejda Diaconu, Nebojsa Bulatovic, Ilyasse Asfalou, Marijan Bosevski, Sigrun Halvorsen, Bożena Sobkowicz, Daniel Ferreira, Antoniu Octavian Petris, Olga Moiseeva, Marco Zavatta, Slobodan Obradovic, Iveta Šimkova, Peter Radsel, Borja Ibanez, Gerhard Wikström, Drahomir Aujesky, Cihangir Kaymaz, Alexander Parkhomenko, Joanna Pepke-Zaba, , 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European respiratory society (ERS) European Heart Journal. ,vol. 41, pp. 543- 603 ,(2020) , 10.1093/EURHEARTJ/EHZ405
Bas van der Veer, Sharon van den Brink, Lisa Wijsman, Gabriel Goderski, Jean-Louis Romette, Joanna Ellis, Maria Zambon, Malik Peiris, Herman Goossens, Chantal Reusken, Marion PG Koopmans, Christian Drosten, Victor M Corman, Olfert Landt, Marco Kaiser, Richard Molenkamp, Adam Meijer, Daniel KW Chu, Tobias Bleicker, Sebastian Brünink, Julia Schneider, Marie Luisa Schmidt, Daphne GJC Mulders, Bart L Haagmans, Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR. Eurosurveillance. ,vol. 25, pp. 2000045- ,(2020) , 10.2807/1560-7917.ES.2020.25.3.2000045
Nanshan Chen, Min Zhou, Xuan Dong, Jieming Qu, Fengyun Gong, Yang Han, Yang Qiu, Jingli Wang, Ying Liu, Yuan Wei, Jia'an Xia, Ting Yu, Xinxin Zhang, Li Zhang, Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study The Lancet. ,vol. 395, pp. 507- 513 ,(2020) , 10.1016/S0140-6736(20)30211-7
Xiaobo Yang, Yuan Yu, Jiqian Xu, Huaqing Shu, Jia'an Xia, Hong Liu, Yongran Wu, Lu Zhang, Zhui Yu, Minghao Fang, Ting Yu, Yaxin Wang, Shangwen Pan, Xiaojing Zou, Shiying Yuan, You Shang, Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respiratory Medicine. ,vol. 8, pp. 475- 481 ,(2020) , 10.1016/S2213-2600(20)30079-5