Analysis of low molecular weight molecules by maldi-ms
作者： Rania Bakry , Rainer Vallant , Guenther Bonn , Christian W. Huck , Zoltan Szabo
DOI:
关键词:
摘要: The invention relates to a process for the analysis of molecules having molecular weight <1500 Da by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), wherein an analyte containing low is applied matrix material, which characterized in that material comprises fullerene-derivatised silica. This allows clear identification small through intensive signals without -related background disturbances.
lens.org参考文章(7)
Rania Bakry, Guenther Bonn, Guenther Stecher, M S Muhammad Ahsan Hashir, Matrix-free maldi mass spectrometry ,(2006)
Terry Marriott, Ramesh Sivarajan, Robert H. Hauge, Carbon nanotubes and their derivatives as matrix elements for the matrix-assisted laser desorption mass spectrometry of biomolecules and sequencing using associated fragmentation United States Patent and Trademark Office. ,(2004)
Muhammad Najam-Ul-Haq, Christian Wolfgang Huck, Isabel Feuerstein, Matthias Rainer, Günther Bonn, Günther Stecher, Georg Schwarzmann, Doris Steinmüller-Nethl, Detlef Steinmüller, Target for laser desorption/ionisation mass spectrometry ,(2005)
Kimberly Prather, Albert J. Schultz, Hiroshi Furutani, Michael V. Ugarov, Maldi-im-ortho-tof mass spectrometry with simultaneaous positive and negative mode detection ,(2004)
Rainer M. Vallant, Zoltan Szabo, Lukas Trojer, Muhammad Najam-ul-Haq, Matthias Rainer, Christian W. Huck, Rania Bakry, Günther K. Bonn, A new analytical material-enhanced laser desorption ionization (MELDI) based approach for the determination of low-mass serum constituents using fullerene derivatives for selective enrichment. Journal of Proteome Research. ,vol. 6, pp. 44- 53 ,(2007) , 10.1021/PR060347M
L. L. Gumanov, G. A. Volkov, A. V. Shastin, B. L. Korsounskii, Preparation and properties of sorbents based on silica gel containing covalently linked fullerene C60 Russian Chemical Bulletin. ,vol. 45, pp. 768- 770 ,(1996) , 10.1007/BF01431294
Andrew R. Barron, Andrew A. Guzelian, Dennis J. Flood, Chemical derivatization of silica coated fullerenes and use of derivatized silica coated fullerenes ,(2006)