The chromosome cycle of prokaryotes.

摘要: In both eukaryotes and prokaryotes, chromosomal DNA undergoes replication, condensation-decondensation segregation, sequentially, in some fixed order. Other conditions, like sister-chromatid cohesion (SCC), may span several events. One set of these transactions within a single cell cycle constitutes the “chromosome cycle”. For many years it was generally assumed that prokaryotic chromosome follows major phases eukaryotic one: -replication-condensation-segregation-(cell division)-decondensation-, with SCC unspecified length. Eventually became evident that, contrast to strictly consecutive eukaryotes, all stages run concurrently. Thus, prokaryotes practice “progressive” segregation separated from replication by brief SCC, three move along at same fast rate. other words, addition forks, there are “segregation forks” chromosomes. Moreover, bulk outside replication-segregation transition stays compacted. I consider possible origins this concurrent outline “nucleoid administration” system organizes dynamic part cycle.