The Chemistry of Bioactive Mesoionic Heterocycles

作者: Masami Kawase , Hiroshi Sakagami , Noboru Motohashi

DOI: 10.1007/7081_2007_096

关键词:

摘要: This review focuses on the latest developments in biologically interesting mesoionic compounds, such as sydnones, sydnonimines, 1,2,3,4-oxatriazolium-5-aminates, and 1,3,4-thiadiazolium-2-aminides, mainly since 2000.

参考文章(76)
Christopher S. Dunkley, Charles J. Thoman, Synthesis and biological evaluation of a novel phenyl substituted sydnone series as potential antitumor agents Bioorganic & Medicinal Chemistry Letters. ,vol. 13, pp. 2899- 2901 ,(2003) , 10.1016/S0960-894X(03)00487-6
R. Gryglewski, E. Marcinkiewicz, J. Robak, Z. Michalska, J. Madej, Mesoionic Oxatriazoles (MOTA): NO-Donating Characteristics and Pharmacology Current Pharmaceutical Design. ,vol. 8, pp. 167- 176 ,(2002) , 10.2174/1381612023396311
Elisabeth Marcos, Serge Adnot, Minh Hien Pham, Anne Nosjean, Bernadette Raffestin, Michel Hamon, Saadia Eddahibi, Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension. American Journal of Respiratory and Critical Care Medicine. ,vol. 168, pp. 487- 493 ,(2003) , 10.1164/RCCM.200210-1212OC
Daryl O Schwenke, James T Pearson, Hirotsugu Tsuchimochi, Hidezo Mori, Mikiyasu Shirai, Exogenous nitric oxide centrally enhances pulmonary reactivity in the normal and hypertensive rat Clinical and Experimental Pharmacology and Physiology. ,vol. 32, pp. 952- 959 ,(2005) , 10.1111/J.1440-1681.2005.4290.X
Nikolaos Pitsikas, Nikolaos Sakellaridis, Memantine and recognition memory: Possible facilitation of its behavioral effects by the nitric oxide (NO) donor molsidomine European Journal of Pharmacology. ,vol. 571, pp. 174- 179 ,(2007) , 10.1016/J.EJPHAR.2007.06.019
H Ferry-Dumazet, M Mamani-Matsuda, M Dupouy, F Belloc, D Thiolat, G Marit, M Arock, J Reiffers, MD Mossalayi, Nitric oxide induces the apoptosis of human BCR-ABL-positive myeloid leukemia cells: evidence for the chelation of intracellular iron. Leukemia. ,vol. 16, pp. 708- 715 ,(2002) , 10.1038/SJ.LEU.2402404
H Kankaanranta, H Vapaatalo, T Metsä-Ketelä, R Andersson, P Vuorinen, E Rydell, E Moilanen, S B Pedersen, T Corell, B Lissau, Pharmacology of mesoionic oxatriazole derivatives in blood, cardiovascular and respiratory systems. Polish Journal of Pharmacology. ,vol. 46, pp. 553- 566 ,(1994)
Vilpo Ja, Metsä-Ketelä T, Vuorinen P, Moilanen E, Vilpo Lm, Mode of cytostatic action of mesoionic oxatriazole nitric oxide donors in proliferating human hematopoietic cells. Anti-cancer Drug Design. ,vol. 12, pp. 75- 89 ,(1997)