Accelerated improvement of alcoholic liver disease with enteral nutrition

摘要: This prospective study compared the effects of tube-fed nutrition with those a regular diet in alcoholic liver disease. The high prevalence malnutrition patients disease requires clarification benefits aggressive nutritional support. Patients were randomly assigned without or supplementation, delivering 1.5 g/kg protein and 167 kJ/kg daily. Comparisons encephalopathy, antipyrine clearance, metabolic rate, biochemical parameters performed weekly for 4 weeks. Sixteen receiving enteral supplementation had half-life (50% vs. 3% reduction), serum bilirubin (25% 0% median encephalopathy scores that improved more rapidly than controls. Initially, 15 controls did not consume adequate calories to meet measured resting energy expenditure. Aggressive intervention accelerated improvement Adverse offset demonstrated 2-cal/mL, casein-based supplement. These findings support use standard, solutions treatment as control condition future studies.