Taking stock of complex trait genetics in mice

摘要: Abstract The mapping of complex trait loci in mice has recently become very popular thanksto dense genetic maps, better approaches to linkage analysis and the continued value mouse as a key model organism for human disease. Neverthelless, ultimate goal remains difficult: identify genes that underlie traits understand their function at molecular level. In assessing prospects current efforts, it helps review findings earlier studies and, despite all technology, be reminded inherent benefits limitations source variation: laboratory mouse. With right perspective should possible geneticists analysing triats take full advantage resources genome project will provide.