A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase

作者: T Banerjee , J B DuHadaway , P Gaspari , E Sutanto-Ward , D H Munn

DOI: 10.1038/SJ.ONC.1210939

关键词:

摘要: … a class of natural products derived from … inhibitors of indoleamine 2,3-dioxygenase (IDO), a pro-toleragenic enzyme that drives immune escape in cancer. Like other known IDO inhibitors…

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