Action of drugs on the aqueous flow in man measured by fluorophotometry.

摘要: A technique is described for measuring the effect on aqueous flow rate in man of drugs topically applied to one eye. Fluorescent measurements are taken from treated and control eyes after both stained with fluorescein by corneal route. mathematical treatment developed which takes account only ratio obtained two eyes. Subsidiary experiments systematically administered make it possible assess changes iris permeability induced drug; these into consideration calculating change rate. Six steroid reactors who reacted Dexamethasone a large rise tension showed no Five normal subjects marked drop guanethidine. Iris decreased increased Experiments pilocarpine gave uncertain results, showing cannot be universally.