Polycyclic Aromatic Hydrocarbons: Multiple Metabolic Pathways and the DNA Lesions Formed
DOI: 10.1002/9783527630110.CH6
关键词:
摘要:
sci-hub.st 参考文章(112)
Qian Ruan, Hye-Young H. Kim, Hao Jiang, Trevor M. Penning, Ronald G. Harvey, Ian A. Blair, Quantification of benzo[a]pyrene diol epoxide DNA‐adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry Rapid Communications in Mass Spectrometry. ,vol. 20, pp. 1369- 1380 ,(2006) , 10.1002/RCM.2457
James A. Swenberg, Patricia B. Upton, Vernon E. Walker, Yoke W. Kow, Su Yin Chiang, Jun Nakamura, Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions Cancer Research. ,vol. 58, pp. 222- 225 ,(1998)
E. L. Cavalieri, E. G. Rogan, Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons Xenobiotica. ,vol. 25, pp. 677- 688 ,(1995) , 10.3109/00498259509061885
S. Nesnow, J. A. Ross, M. J. Mass, G. D. Stoner, Mechanistic relationships between DNA adducts, oncogene mutations, and lung tumorigenesis in strain A mice. Experimental Lung Research. ,vol. 24, pp. 395- 405 ,(1998) , 10.3109/01902149809087376
Marnett Lj, Martin Mv, Shimada T, Guengerich Fp, Pruess-Schwartz D, Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. Cancer Research. ,vol. 49, pp. 6304- 6312 ,(1989)
T. Shimada, Yune-Fang Ueng, H. Yamazaki, F. P. Guengerich, M. Mimura, N. Wakamiya, Y. Inui, Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs. Drug Metabolism and Disposition. ,vol. 24, pp. 515- 522 ,(1996)
D. E. Ryan, D. R. Thakker, D. M. Jerina, W. Levin, H. Yagi, K. P. Vyas, M. Nordqvist, P. E. Thomas, A. H. Conney, Metabolism of Chrysene and Phenanthrene to Bay-Region Diol Epoxides by Rat Liver Enzymes Molecular Pharmacology. ,vol. 19, pp. 168- 178 ,(1981)
ROLAND E. LEHR, SUBODH KUMAR, WAYNE LEVIN, ALEXANDER W. WOOD, RICHARD L. CHANG, ALLAN H. CONNEY, HARUHIKO YAGI, JANE M. SAYER, DONALD M. JERINA, The Bay Region Theory of Polycyclic Aromatic Hydrocarbon Carcinogenesis American Chemical Society. pp. 63- 84 ,(1985) , 10.1021/BK-1985-0283.CH004
Wayne Levin, Jaime Kapitulnik, Donald M. Jerina, Haruhiko Yagi, Allan H. Conney, Peter G. Wislocki, Tumorigenicity studies with diol-epoxides of benzo(a)pyrene which indicate that (+/-)-trans-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene is an ultimate carcinogen in newborn mice. Cancer Research. ,vol. 38, pp. 354- 358 ,(1978)
T E Smithgall, R G Harvey, T M Penning, Regio- and stereospecificity of homogeneous 3 alpha-hydroxysteroid-dihydrodiol dehydrogenase for trans-dihydrodiol metabolites of polycyclic aromatic hydrocarbons. Journal of Biological Chemistry. ,vol. 261, pp. 6184- 6191 ,(1986) , 10.1016/S0021-9258(19)84546-5