[8] Hysteretic enzymes

摘要: Publisher Summary This chapter discusses that the concept enzymic reactions demonstrate linear reaction rates and, therefore, progress curves, after a very rapid attainment of steady state, dates to early formulations enzyme kinetics. It also analysis steady-state kinetics in such system, possibilities producing cooperative monomeric enzyme, possibility altering kinetic cooperativity an oligomeric and correlation between enzymes showing hysteretic responses possessing their The presents unified picture enzymes, areas agreement different workers, details certain specific models make them attractive explain particular enzymes. Two aspects these systems discussed are (slow) process itself its relationship Although two related through models, they must be remembered as concepts; hysteresis may occur without cooperativity, but (by this mechanism) requires molecular transition.