An Evaluation of DFP32 and Cr51 as Methods of Measuring Red Cell Life Span in Man

作者: MARTIN J. CLINE , NATHANIEL I. BERLIN

DOI: 10.1182/BLOOD.V22.4.459.459

关键词:

摘要: DFP32 or Cr51 red cell survival studies were performed in 39 patients with hematologic disorders. In each case the erythrocyte life span was also determined using C14-labeled glycine technic. Good agreement found between data obtained by and method. The T½ failed to reflect moderate shortening of a significant number cases when 25 day half-time taken as lower limit normal. occasional discrepancy spans labeled halftime is probably result limitations prevalent method analysis wide range elution rates disease. Because its simplicity reliability, technics appears be choice for determination survival.

参考文章(16)
Helen Paputchis, Peter Fredrik Hjort, Barbara Cheney, Labeling of red blood cells with radioactive diisopropylfluorophosphate (DFP32): evidence for an initial release of label. Journal of Laboratory and Clinical Medicine. ,vol. 55, pp. 416- 424 ,(1960) , 10.5555/URI:PII:0022214360900949
J. G. Eernisse, J. J. VAN Rood, Erythrocyte Survival‐Time Determinations with the Aid of DF32P British Journal of Haematology. ,vol. 7, pp. 382- 404 ,(1961) , 10.1111/J.1365-2141.1961.TB00348.X
Seymour J. Gray, Kenneth Sterling, THE TAGGING OF RED CELLS AND PLASMA PROTEINS WITH RADIOACTIVE CHROMIUM Journal of Clinical Investigation. ,vol. 29, pp. 1604- 1613 ,(1950) , 10.1172/JCI102403
DAVID G. NATHAN, NATHANIEL I. BERLIN, Studies of the Production and Life Span of Erythrocytes in Myeloid Metaplasia Blood. ,vol. 14, pp. 668- 682 ,(1959) , 10.1182/BLOOD.V14.6.668.668
MARTIN J. CLINE, NATHANIEL I. BERLIN, Red Blood Cell Life Span Using DFP32 as a Cohort Label Blood. ,vol. 19, pp. 715- 723 ,(1962) , 10.1182/BLOOD.V19.6.715.715