Tile-Based DNA Nano-assemblies

摘要: Tile-based DNA nanostructures have played an important role in the evolution of field structural nanotechnology over last three decades. These structures are formed using multiple short synthetic oligonucleotide strands that specifically designed to self-assemble into desired configurations. Successful assembly a variety planar tiles has been demonstrated including crossover tiles, multi-armed weave etc. then used form one- and two-dimensional arrays or lattices. In addition, three-dimensional tile-based developed helix bundle tubes, finite-sized closed polyhedral structures, crystalline lattice. This chapter chronicles progress thus far design synthesis nano-assemblies. Furthermore, it details steps involved successful design, synthesis, characterization such structures. It also reviews applications these molecular computation programmed other nanoscale materials as proteins, metallic nanoparticles, aptamers.