PINP en pacientes con insuficiencia hepática: Comparación de dos métodos de medida y asociación con diferentes parámetros bioquímicos

作者: S. Guadalix , L. Martínez-Conde , G. Martínez Díaz-Guerra , C. Vargas , F. Hawkins

DOI: 10.4321/S1889-836X2013000100004

关键词:

摘要: , QDR 4500) in the lumbar spine and femoral neck. The compa- rison between two methods was carried out using a Bland-Altman Passing'Bablok analysis. Results: R-PINP showed higher values than IDS-PINP (85.03 ± 56.67 vs. 55.22 32.81 ng/mL, p<0,001). correlation r= 0.81 (p<0.01) Passing-Bablok regression analy- sis Y = 0.570 (0.475-0.669) X + 7.724 (2.130-12.542). Conclusion: There is good patients with hepatic insufficiency, although not proportional or interchangeable.

参考文章(23)
J.A Clowes, R.A Hannon, T.S Yap, N.R Hoyle, A Blumsohn, R Eastell, Effect of feeding on bone turnover markers and its impact on biological variability of measurements. Bone. ,vol. 30, pp. 886- 890 ,(2002) , 10.1016/S8756-3282(02)00728-7
Marja-Kaisa Koivula, Jill Richardson, Aila Leino, Heikki Valleala, Katie Griffiths, Alex Barnes, Yrjö T. Konttinen, Martha Garrity, Juha Risteli, Validation of an automated intact N-terminal propeptide of type I procollagen (PINP) assay. Clinical Biochemistry. ,vol. 43, pp. 1453- 1457 ,(2010) , 10.1016/J.CLINBIOCHEM.2010.09.019
Marja-Kaisa Koivula, Leila Risteli, Juha Risteli, Measurement of aminoterminal propeptide of type I procollagen (PINP) in serum. Clinical Biochemistry. ,vol. 45, pp. 920- 927 ,(2012) , 10.1016/J.CLINBIOCHEM.2012.03.023
P Garnero, P D Delmas, Assessment of the serum levels of bone alkaline phosphatase with a new immunoradiometric assay in patients with metabolic bone disease The Journal of Clinical Endocrinology and Metabolism. ,vol. 77, pp. 1046- 1053 ,(1993) , 10.1210/JCEM.77.4.8104954
M. Diaz Curiel, J. L. Carrasco de la Peña, J. Honorato Perez, R. Perez Cano, A. Rapado, I. Ruiz Martinez, Study of bone mineral density in lumbar spine and femoral neck in a Spanish population Osteoporosis International. ,vol. 7, pp. 59- 64 ,(1997) , 10.1007/BF01623462
Lourdes Gilfraguas, Sonsoles Guadalix, Guillermo Martinez, Esteban Jodar, Jesus Vara, Miguel Angel Gomez-Sanchez, Juan Delgado, Javier De La Cruz, David Lora, Federico Hawkins, Bone Loss after Heart Transplant: Effect of Alendronate, Etidronate, Calcitonin, and Calcium plus Vitamin D3 Progress in Transplantation. ,vol. 22, pp. 237- 243 ,(2012) , 10.7182/PIT2012969
Sydney Lou Bonnick, Lee Shulman, Monitoring osteoporosis therapy: bone mineral density, bone turnover markers, or both? The American Journal of Medicine. ,vol. 119, ,(2006) , 10.1016/J.AMJMED.2005.12.020
J. Martin Bland, DouglasG. Altman, Statistical methods for assessing agreement between two methods of clinical measurement. The Lancet. ,vol. 327, pp. 307- 310 ,(1986) , 10.1016/S0140-6736(86)90837-8
M.-K. Koivula, V. Ruotsalainen, M. Bjorkman, S. Nurmenniemi, R. Ikaheimo, K. Savolainen, A. Sorva, J. Risteli, Difference between total and intact assays for N-terminal propeptide of type I procollagen reflects degradation of pN-collagen rather than denaturation of intact propeptide: Annals of Clinical Biochemistry. ,vol. 47, pp. 67- 71 ,(2010) , 10.1258/ACB.2009.009110