Feasibility of a rapid dipstick antigen-capture assay for self-testing of travellers' malaria

摘要: SummaryThis open comparative study sought to determine whether, and with what level of instruction, travellers can successfully use interpret the rapid whole blood malaria diagnostic test, ParaSight F. 160 visitors Zurich University Travel Clinic took part in study. One group received written instructions only, while another was given combined oral on how test their own for infection a series 5 prepared strips. Each volunteer also completed questionnaire targeted at assessing performance using diagnostic, interpretation results acceptability concept self-testing infection. The main outcome measures were successful correct strips test. In which only instructions, 60/80 (75%) successful, whilst 72/80 (90%) performed (P < 0.02). Overall, 565 (70.6%) correctly 165 (20.6%) incorrectly interpreted 113 (14.1%) false negative interpretations. No strip as positive. Seventy (8.8%) not interpreted. Some 91.9% all candidates would such if it available. While is possible lay persons perform poses problem. particular, proportion interpretations unacceptable. A combination leads significantly higher performance. If be made available general public, must concise foolproof endpoint clearly defined, currently more suitable trained laboratory personnel. meantime other candidate diagnostics have become these should now assessed suitability context travellers' malaria.