Maxillofacial and Axial/Appendicular Giant Cell Lesions: Unique Tumors or Variants of the Same Disease?—A Comparison of Phenotypic, Clinical, and Radiographic Characteristics
作者： Cory M Resnick , Jeffrey Margolis , Srinivas M Susarla , Joseph H Schwab , Francis J Hornicek
DOI: 10.1016/J.JOMS.2009.04.106
关键词:
摘要: Purpose The relationship between giant cell lesions (GCLs) of the maxillofacial (MF) skeleton and those axial/appendicular (AA) has been long debated. present study compared clinical radiographic characteristics subjects with MF AA GCLs. Materials Methods This was a retrospective cohort patients treated for GCLs at Massachusetts General Hospital from 1993 to 2008. predictor variables included tumor location (MF or AA) behavior (aggressive nonaggressive). outcome demographic, clinical, parameters, treatments, outcomes. Descriptive bivariate statistics were computed, P ≤ .05 considered significant. Results sample 93 subjects: 45 (38 aggressive 7 nonaggressive) 48 (30 18 Comparing GCLs, presented younger (P Conclusions These results suggest that represent similar, if not same, disease. nonaggressive subgroups, more similarities found than when evaluating without stratification by behavior. remaining differences could be explained likelihood tumors are diagnosed earlier because facial exposure dental screening examinations radiographs.
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