Utility of prechemotherapy echocardiographical assessment of cardiac abnormalities

作者: Narayan V. Karanth , Amitesh Roy , Majo Joseph , Carmine de Pasquale , Christos Karapetis

DOI: 10.1007/S00520-010-1054-Z

关键词:

摘要: Echocardiography provides both morphological and functional information offering a potential advantage over nuclear medicine gated blood pool scans which only estimate ejection fraction. This additional may be relevant to management of patients receiving potentially cardiotoxic cancer treatment. We retrospectively audited all prechemotherapy echocardiograms (ECHO) ordered by medical oncologists at our institution 36 months period. The primary objective was determine the frequency cardiac abnormality detection on initial ECHO. also looked clinically abnormalities other than fraction including diastolic dysfunction, intracardiac shunts, moderate–severe valvular abnormalities, pulmonary hypertension, ventricular hypertrophy, pericardial effusion, wall motional dysfunction/dilatation, tumours congenital anomalies. Baseline ECHOs were analysed in 217 consecutive patients. Female comprised 89% population, majority had breast (75.5%). median age time ECHO 55 years (range, 16 87); 13.4% least one Systolic moderate dysfunctions seen 5% 2.7%, respectively. Aortic stenosis five (2.3%) Atrial septal defects two patients, mitral regurgitations left atrial tumour patient. A total 7.4% would not have been detected scan (GBPS). resulted change chemotherapy plan 2.8% referral cardiology 3.7%. Our retrospective analysis suggests that can provide more useful clinical GBPS, impact

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