The impact of malnutrition in morbidity and mortality in stable haemodialysis patients. Spanish Cooperative Study of Nutrition in Hemodialysis.

作者: R Marcen

DOI: 10.1093/NDT/12.11.2324

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摘要: BACKGROUND When assessed by single biochemical measurements, malnutrition in dialysis patients is associated with increased mortality, but there are few data evaluating abnormalities anthropometry or composite nutritional scores and outcome. The aim of our study was to ascertain the prevalence severity 761 stable from 20 haemodialysis centres its influence morbidity mortality after one year follow-up. METHODS Malnutrition estimated scoring four anthropometric indexes; body mass index (BMI), triceps skinfold thickness (TSF), mid-arm circumference (MAC), muscle (MAMC); three measurements; serum albumin, transferrin total lymphocyte count; clinical examination. Mortality hospitalizations were collected prospectively during RESULTS A moderate/severe degree presented 51.6% male 46.3% female patients. TSF moderate-severely decreased 41% without differences between males females. MAMC moderately 19.8% 8.1% females (P 65 years (OR = 1.96, CI: 1.22-3.14), sex 1.95, 1.24-3.07), comorbidity 1.23, 1.03-1.45), time on 1.13, 1.08-1.18), duration 0.73, 0.63-0.85) PCR related ideal weight 0.17, 0.06-0.50). After 1 follow-up, 442 available. 68 died (15.4%) cardiovascular diseases being most frequent cause death (57.3% cases). predictors were: age 1.06, 1.03-1.09), disease 2.13, 1.19-3.83), neurological 2.96, 1.41-6.15), nephroangiosclerosis 2.34, 1.10-4.98) count 0.93, 0.87-0.98). Hospitalization needed 44% index, albumin predictive factors hospitalization. CONCLUSIONS Protein-calorie Fat depletion predominated both sexes. Duration protein catabolic rate only predictor which could be influenced a intervention. Morbidity appeared strongest mortality. measurements respectively. Therefore, can not definitively stated.

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