Validation of cerebrospinal fluid findings in aneurysmal subarachnoid hemorrhage

摘要: Abstract Background Recently proposed cutoff criteria for cerebrospinal fluid (CSF) analyses might safely exclude a diagnosis of aneurysmal subarachnoid hemorrhage (aSAH). Objective The objective this study was to examine the sensitivity CSF red blood cell (RBC) count greater than 2000 × 10 6 /L (ie, RBCs per microliter) or presence visible xanthochromia in identifying patients with aSAH. Methods We identified retrospective case series diagnosed aSAH after lumbar puncture (LP) an integrated health delivery system between January and June 2013 by chart review. All had at least 1 cerebral aneurysm that treated neurosurgical endovascular intervention during index hospitalization. lowest RBC used validation analysis. Cerebrospinal color determined visual inspection. Xanthochromia defined as pink, orange, yellow pigmentation supernatant. Results Sixty-four met inclusion criteria. Of these, 17 (33%) 52 underwent LP within 12 hours headache onset, 49 (84%) 58 exhibited xanthochromia. median 63250 /L. 96.9% (95% confidence interval, 89.3%-99.1%). Additional consideration resulted 100% 94.3%-100%). Conclusions either xanthochromia, increasing likelihood strategy may identify who warrant further investigation cause hemorrhage.