Treatment of Cutaneous Lupus Erythematosus: Review and Assessment of Treatment Benefits Based on Oxford Centre for Evidence-based Medicine Criteria.

摘要: The treatment of cutaneous lupus erythematosus is centered upon formulating a regimen topical and systemic therapies designed to reduce disease activity minimize cosmetic damage. Sun avoidance sunscreen are important preventative measures proven exacerbations. Limited typically managed with corticosteroids or calcineurin inhibitors. Antimalarial therapy the gold standard therapy. Many other treatments have been studied in patients recalcitrant erythematosus, their use must be evaluated based on individual risk-benefit concerns. R-salbutamol pulsed dye laser effective alternatives. Additional agents include retinoids, immunosuppressants, immunomodulators, biologics, experimental novel modes action. According Oxford Centre for Evidence-based Medicine criteria evaluating strength evidence supporting an measure, no has achieved Level 1 status. This demonstrates need randomized, controlled trials systematic reviews all interventions order meet increasing standards demand evidence-based practice.