Nutritional cerebellar degeneration, with comments on its relationship to Wernicke disease and alcoholism

摘要: Nutritional cerebellar degeneration occurs in alcoholism and other states that predispose to malnutrition, such as gastric bypass surgery. Gait ataxia is the principal clinical manifestation. Ataxia of lower limbs not uncommon, but upper extremity nystagmus are rare. Atrophy anterior superior vermis primary pathological manifestation established disease. Typically, onset subacute. This disease part spectrum Wernicke-Korsakoff syndrome, i.e. Wernicke It may occur with lesions or isolation. Rarely, florid disease, be hemorrhagic. Active should treated thiamine same way one treats Clinicopathologic correlation this has provided best evidence important coordinating bipedal locomotion.