A Methodology for Estimating Human Exposure to Perfluorooctanoic Acid (PFOA): A Retrospective Exposure Assessment of a Community (1951–2003)

摘要: Perfluorooctanoic acid (PFOA) is a persistent chemical that was recently shown to be widely distributed in the ambient environment. Because of concerns about possible adverse health effects on persons exposed PFOA, retrospective exposure assessment conducted for population 50,000 who reside near one facilities where this used. No similar study any with properties PFOA had ever been performed; thus, several novel methods were developed and applied analysis. Historical records emissions from facility basis estimates potential intake by residents over past 53 yr. Various well-accepted environmental models dynamically combined order estimate concentrations all relevant media including air, surface soil, drinking water, homegrown vegetables. Following considerable analyses, particulate deposition air soil s...