De-differentiation and re-differentiation of somatic cells and production of cells for cell therapies

作者: Raymond Page , Tanja Dominko

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摘要: The invention provides a method for effecting the trans-differentiation of somatic cell, i.e., conversion cell one type into different type. is practiced by culturing in presence at least agent selected from group consisting (a) cytoskeletal inhibitors and (b) acetylation, (c) methylation, also agents or conditions that induce differentiation to useful producing histocompatible cells therapy.

参考文章(42)
Keith Cauley, Valery G. Kukekov, Human oligodendroglial progenitor cell line ,(1995)
Rosemary A. Fricker, Melissa K. Carpenter, Christian Winkler, Corinne Greco, Monte A. Gates, Anders Björklund, Site-Specific Migration and Neuronal Differentiation of Human Neural Progenitor Cells after Transplantation in the Adult Rat Brain The Journal of Neuroscience. ,vol. 19, pp. 5990- 6005 ,(1999) , 10.1523/JNEUROSCI.19-14-05990.1999
Jeffrey M. Betthauser, Gail L. Jurgella, Nikolai S. Strelchenko, Marvin M. Pace, Michael D. Bishop, Method of cloning bovines using reprogrammed non-embryonic bovine cells ,(1999)
James Leushner, Marina T. Larson, May Hui, James M. Dunn, Method for single-tube sequencing of nucleic acid polymers ,(1996)
Philippe Collas, James M. Robl, Eddie Sullivan, P. Kasinathan, Methods for cloning mammals using reprogrammed donor chromatin or donor cells ,(2001)