Surgery of gastric cancer and esophageal cancer: Does age matter?

摘要: Introduction In the past, elderly patients with upper GI cancers were excluded from surgery or multimodal treatment only due to their advanced age. In an aging society this way of patient selection seems be questionable. The aim retrospective exploratory study was investigate how cancer over age 70 years differ younger in postoperative course and which parameters influence overall survival older populations. Patients Methods From 2002 2012 1,005 underwent resection esophageal gastric at University Heidelberg. 272 than analyzed subgroups (70–74 years: n = 146; 75–79 n = 82; 80 older: n = 44). Patients compared under (n = 733) focus on differences characteristics outcome. Statistical analyses made retrospectively a prospective database. Results Fewer treated neoadjuvantly (  70 24.7%, P  19.9%,  80 16.7 vs. 20.5% < 70 6.0%, P = 0.002). Conclusions An exclusion surgical therapy general not justified. However, decision for should caution. pNM-categories R0-resection remain most important predictive factors all subgroups. No benefit neoadjuvant found, while women survived longer men. concerning (radio) chemotherapy individually each patient. © 2015 Wiley Periodicals, Inc.