Vitamin D deficiency and its relationship to cancer stage in patients who underwent thyroidectomy for papillary thyroid carcinoma.

摘要: Abstract Purpose As imaging technology improves and more thyroid nodules malignancies are identified, it is important to recognize factors associated with malignancy poor prognosis. Vitamin D has proven useful as a prognostic tool for other cancers may be similarly in cancer. This study explores the relationship of papillary carcinoma stage while accounting socioeconomic covariates. Materials methods The medical records all patients who underwent thyroidectomy at one institution between 2000 2015 were reviewed. Subjects non-papillary cancer pathology, prior malignancy, without levels excluded. remaining 334 patient examined stage, levels, deficiency listed history, demographic comorbid factors. Results laboratory values showed no significant (p = 0.871), but documented record likely have advanced disease (28.6% versus 14.7%; p = 0.028). also had lower 25-hydroxyvitamin nadirs (21.5 ng/mL 26.5 ng/mL, p = 0.008) on supplementation (92.6% 41.8%, p  Conclusions results suggest that value negative indicator pre-operative evaluation less useful. because modifiable. While different racial subgroups rates deficiency, neither race nor status correlation stage.