Spatiotemporal modelling of viral infection dynamics

作者: Catherine Beauchemin

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摘要: Viral kinetics have been studied extensively in the past through use of ordinary differential equations describing time evolution diseased state a spatially well-mixed medium. However, emerging spatial structures such as localized populations dead cells might affect spread infection, similar to manner which counter-fire can stop forest fire from spreading. In first phase project, simple two-dimensional cellular automaton model viral infections was developed. It validated against clinical immunological data for uncomplicated influenza A and shown be accurate enough adequately

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