Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
作者： David D. Ho , Avidan U. Neumann , Alan S. Perelson , Wen Chen , John M. Leonard
DOI: 10.1038/373123A0
关键词:
摘要: Abstract Treatment of infected patients with ABT-538, an inhibitor of the protease of human immuno-deficiency virus type 1 (HIV-1), causes plasma HIV-1 levels to decrease …
unirioja.es
harvard.edu
nature.com
sci-hub.se 参考文章(14)
P Simmonds, P Balfe, J F Peutherer, C A Ludlam, J O Bishop, A J Brown, Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers. Journal of Virology. ,vol. 64, pp. 864- 872 ,(1990) , 10.1128/JVI.64.2.864-872.1990
Janet Embretson, Mary Zupancic, Jorge L. Ribas, Alien Burke, Paul Racz, Klara Tenner-Racz, Ashley T. Haase, Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS Nature. ,vol. 362, pp. 359- 362 ,(1993) , 10.1038/362359A0
ASHLEY T. HAASE, The Role of Active and Covert Infections in Lentivirus Pathogenesis Annals of the New York Academy of Sciences. ,vol. 724, pp. 75- 86 ,(1994) , 10.1111/J.1749-6632.1994.TB38897.X
Simon Wain-Hobson, Viral burden in AIDS Nature. ,vol. 366, pp. 22- 22 ,(1993) , 10.1038/366022B0
B. Patterson, M Till, P Otto, C Goolsby, M. Furtado, L. McBride, S. Wolinsky, Detection of HIV-1 DNA and messenger RNA in individual cells by PCR-driven in situ hybridization and flow cytometry Science. ,vol. 260, pp. 976- 979 ,(1993) , 10.1126/SCIENCE.8493534
Simon Wain-Hobson, The fastest genome evolution ever described: HIV variation in situ Current Opinion in Genetics & Development. ,vol. 3, pp. 878- 883 ,(1993) , 10.1016/0959-437X(93)90008-D
M Piatak, M. Saag, L. Yang, S. Clark, J. Kappes, K. Luk, B. Hahn, G. Shaw, J. Lifson, High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR Science. ,vol. 259, pp. 1749- 1754 ,(1993) , 10.1126/SCIENCE.8096089
Jean Claude Ameisen, Andre Capron, Cell dysfunction and depletion in AIDS: the programmed cell death hypothesis Immunology Today. ,vol. 12, pp. 102- 105 ,(1991) , 10.1016/0167-5699(91)90092-8
Giuseppe Pantaleo, Cecilia Graziosi, James F. Demarest, Luca Butini, Maria Montroni, Cecil H. Fox, Jan M. Orenstein, Donald P. Kotler, Anthony S. Fauci, HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease Nature. ,vol. 362, pp. 355- 358 ,(1993) , 10.1038/362355A0
R. Weiss, How does HIV cause AIDS? Science. ,vol. 260, pp. 1273- 1279 ,(1993) , 10.1126/SCIENCE.8493571