A functional hypothesis for LGN-V1-TRN connectivities suggested by computer simulation.

作者: John Bickle , Marica Bernstein , Matt Heatley , Cindy Worley , Samantha Stiehl

DOI: 10.1023/A:1008805922693

关键词:

摘要: We employ computer simulation to investigate the function of neural circuitries between thalamic sensory relay nuclei, primary cortices, and reticular nucleus (TRN). Computational similarities exist these circuits architecture a simple artificial network. impose processing parameters on this network in keeping with anatomical physiological details mammalian geniculo-cortical visual pathway, then run task involving multiple simultaneous inputs from simulated field. After two three loops through simulation, activity cortical units whose receptive fields include stronger stimulus remains constant, while other activated by weaker stimuli declines toward resting values. These results suggest that modeled circuitry functions “prime” selective attentional mechanisms further up streams specific portions total stimulus. Besides extending existing models evidence about circuits, our also provide physiologists predicted profiles elements system for not yet studied experimentally.

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