Mechanism of DNA Replication in Drosophila Chromosomes: Structure of Replication Forks and Evidence for Bidirectionality

作者: H. J. Kriegstein , D. S. Hogness

DOI: 10.1073/PNAS.71.1.135

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摘要: Abstract The replicating chromosomal DNA in Drosophila melanogaster cleavage nuclei has been visualized the electron microscope as a serial array of closely spaced replicated regions created by pairs diverging replication forks. The fine structure forks is very similar to that observed for bidirectionally bacteriophage DNAs. However, mean length single-stranded gaps less than 200 nucleotide residues, much shorter phage This difference gap corresponds size Okazaki fragments from and phage.

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