Regulation of the Biosynthesis of the Branched-Chain Amino Acids

摘要: Publisher Summary This chapter presents the regulation of biosynthesis branched-chain amino acids. For a long time, acids have been considered under common heading in biochemistry textbooks. The basis for this grouping was solely their structural relationship as before advent isotopie tracer techniques and mutant methodology, so little known catabolism nothing biosynthesis. On catabolism, they might separately studies with diabetic dog revealed that leucine ketogenic acid, valine glycogenic, isoleucine both. With elucidation biosynthetic pathways leading to by isotopie, enzymatic, genetic studies, it became quite clear three were indeed closely related each other respect