Response surface analysis and simulation as a tool for bioprocess design and optimization

作者: S.J. Kalil , F. Maugeri , M.I. Rodrigues

DOI: 10.1016/S0032-9592(99)00101-6

关键词:

摘要: … equations using experimental parameters have been … optimization using factorial design methodology associate with a deterministic modeling of the process and computer simulations. …

参考文章(25)
I. Sa-Correia, N. Van Uden, Ethanol-induced death of Saccharomyces cerevisiae at low and intermediate growth temperatures Biotechnology and Bioengineering. ,vol. 28, pp. 301- 303 ,(1986)
M. I. Rodrígues, R. Maciel Filho, F. Maugeri, The Control Problem for Protein Separation by the Continuous Affinity Recycling Extraction Process Springer, Dordrecht. pp. 321- 328 ,(1994) , 10.1007/978-94-017-0641-4_44
E. Batista, M.I. Rodrigues, A.J. Meirelles, Optimization of a secondary reflux and vaporization (SRV) distillation process using surface response analysis Computers & Chemical Engineering. ,vol. 22, pp. 737- 740 ,(1998) , 10.1016/S0098-1354(98)00137-9
M.I. Rodrigues, C.A. Zaror, F. Maugeri, J.A. Asenjo, Dynamic modelling, simulation and control of continuous adsorption recycle extraction Chemical Engineering Science. ,vol. 47, pp. 263- 269 ,(1992) , 10.1016/0009-2509(92)80220-7
R. L. PLACKETT, J. P. BURMAN, THE DESIGN OF OPTIMUM MULTIFACTORIAL EXPERIMENTS Biometrika. ,vol. 33, pp. 305- 325 ,(1946) , 10.1093/BIOMET/33.4.305
M.I. Rodrigues, R.Maciel Filho, F. Maugeri, Optimization of a process of continuous enzyme purification by surface response analysis Food Control. ,vol. 4, pp. 144- 148 ,(1993) , 10.1016/0956-7135(93)90301-4
G. Dasari, E. Keshavarz, M. A. Connor, N. B. Pamment, A reliable method for detecting the intracellular accumulation of fermentation products: Application to intracellular ethanol analysis Biotechnology Letters. ,vol. 7, pp. 541- 546 ,(1985) , 10.1007/BF01026442
W A Bazaraa, E E Hassan, Response surface optimization for the continuous glucose isomerization process Journal of Industrial Microbiology & Biotechnology. ,vol. 17, pp. 100- 103 ,(1996) , 10.1007/BF01570051
Harold G. Monbouquette, Modeling high-biomass-density cell recycle fermentors. Biotechnology and Bioengineering. ,vol. 39, pp. 498- 503 ,(1992) , 10.1002/BIT.260390504