Arsenic trioxide and acute promyelocytic leukemia: clinical and biological.
作者： Z. Chen , W. -L. Zhao , Z. -X. Shen , J. -M. Li , S. -J. Chen
DOI: 10.1007/978-3-540-34594-7_8
关键词:
摘要: Arsenic has recently been identified as an effective drug in the treatment of newly diagnosed and relapsed acute promyelocytic leukemia. Indeed, arsenic trioxide combined with all-trans retinoic acid shows a synergistic effect. Mechanistically, targets key leukemogenic protein PML-RARα, setting up new example molecular target-based cancer therapy.
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