Minimal access versus open transforaminal lumbar interbody fusion: meta-analysis of fusion rates.

摘要: Study design A quantitative meta-analysis was conducted on published studies reporting fusion rates after open or minimally invasive/mini-open transforaminal lumbar interbody (TLIF) procedures for single multilevel degenerative disease including stenosis with spondylolisthesis and disc disease. Objectives The primary aim of this study to establish benchmark TLIF invasive (mTLIF) based studies. secondary goal review complication both approaches. Summary background data Lumbar the treatment has evolved from a purely posterior noninstrumented approach combination anterior and/or surgery instrumentation. increasingly popular advanced incorporate spinal techniques. There currently exist no controlled comparisons between mTLIF. Methods Medline search performed identify rate mTLIF database patient demographic information, rate, created. Fusion were pooled according whether technique. Publication bias assessed Egger's test, adjustments using Duval Tweedie's Trim Fill algorithm. Results Twenty-three articles identified that fit inclusion criteria. In each 23 studies, pedicle fixation evaluated radiograph computed tomography scan at minimum 6-month follow-up. Overall, included 1028 patients, 46.8% which female. mean age all patients 49.7 (range, 38-64.9), follow-up interval assessment 26.6 months 6-46 months). usage recombinant bone morphologic protein higher in group (50% vs. 12%). Mean 16 (716 patients) 90.9%, whereas 8 (312 94.8%. Complication 12.6% 7.5% mTLIF, respectively. Conclusion are relatively high similar ranges. also similar, trend toward having lower rate. This analysis provides clear benchmarks spine surgeons.