A randomised comparison of two inactivated hepatitis A vaccines, Avaxim and Vaqta, given as a booster to subjects primed with Avaxim.

作者: Paul Clarke , Nicholas Kitchin , Frédéric Souverbie

DOI: 10.1016/S0264-410X(01)00195-5

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摘要: Abstract To investigate whether Vaqta™ may be used as a booster in subjects primed with Avaxim™, 127 adults 6 months previously Avaxim™ were randomised to receive either or booster. Prior the all seropositive. Geometric mean antibody titres increased from 496 7262 mIU/mL 1 month after receiving and 325 5131 Both vaccines well tolerated; 20.3% of experienced local reaction, compared 39.7% those Avaxim™. Systemic reactions reported by 15.6% 14.3%

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